What is PGT-A?
Pre implantation genetic testing for aneuploidy refers to a process in which a few cells from the tropho ectoderm of the blastocyst are biopsied and sent for genetic analysis
Why is it done?
This will identify if the embryo is genetically normal (euploid) or genetically abnormal(aneuploid)
How is it done?
The embryo is formed by the process of IVF or ICSI as usual and allowed to grow till day 5.
Then a few cells (about 5-10) are removed by use of laser and sent for genetic analysis
What is mosaicism?
It is the condition where more than one type of cells are present in the same embryo-that is both euploid and aneuploid cells hence there maybe the chance for false positive or false negative results depending on which cells were taken in the biopsy
Who is it advised for?
It is advised for mainly older age couples, recurrent implantation failures, recurrent pregnancy loss. testing for specific gene disorders which run in the family-this is called as PGT-M
Pre implantation genetic testing for aneuploidy refers to a process in which a few cells from the tropho ectoderm of the blastocyst are biopsied and sent for genetic analysis
This will identify if the embryo is genetically normal (euploid) or genetically abnormal(aneuploid)
The embryo is formed by the process of IVF or ICSI as usual and allowed to grow till day 5
Then a few cells (about 5-10)are removed by use of laser and sent for genetic analysis
It is the condition where more than one type of cells are present in the same embryo-that is both euploid and aneuploid cells
Hence there maybe the chance for false positive or false negative results depending on which cells were taken in the biopsy
It is advised for mainly