24/7 Support

We are always open at KK Nagar

PGT-A

Best PGT-A Procedure: Our Expertise in Chennai

Kanaa Fertility Centre is one of the top-rated clinics in Chennai providing PGT-A procedures. Our team of experts helps patients interested in knowing what is PGT-A and the benefits of PGT-A procedure before the treatment. Book Now!

What is PGT-A?

Preimplantation genetic testing entails sampling a few cells from the trophoectoderm of a blastocyst and having them genetically analyzed. This procedure identifies which embryos are chromosomally normal and transferable. Embryo genetic testing through PGT-A enables physicians to select embryos with the highest chance for successful implantation while minimizing miscarriage risk.

Why is PGT-A Performed?

PGT-A testing is conducted to:

  • Detect genetically normal (euploid) embryos.

     

  • Identify genetically abnormal (aneuploid) embryos.

     

  • Improve IVF implantation success rates.

     

  • Decrease the risk of repeated pregnancy loss.

     

It is especially beneficial for couples struggling with infertility, maternal age, or repeat implantation failure.

How is PGT-A Performed?

The process of IVF genetic testing involves:

  1. Embryo Formation – Embryos are grown through IVF or ICSI and allowed to develop to the blastocyst stage (Day 5).
  2. Blastocyst Biopsy – Using a laser, 5–10 cells are gently removed from the trophoectoderm of a blastocyst.
  3. Genetic Analysis – The biopsied cells undergo genetic analysis in a specialized lab to determine euploid or aneuploid status.

What is Mosaicism?

Mosaicism is the presence of more than one type of cell in the same embryo — both euploid and aneuploid. This may lead to false positive or false negative results depending on which cells are sampled during the biopsy. PGT-A testing accounts for this, and genetic counseling is recommended for result interpretation.

Benefits of PGT-A

  • Enables selection of chromosomally normal embryos for transfer.

  • Increases chances of successful implantation.

  • Reduces risk of miscarriage and genetic disorders.

  • Provides detailed embryo genetic testing results for informed decision-making.

Who is PGT-A Advised For?

PGT-A IVF is recommended for:

  • Older-age couples seeking IVF.
  • Individuals experiencing recurrent implantation failure.
  • Couples with a history of recurrent pregnancy loss.
  • Families with known genetic disorders (for targeted testing, known as PGT-M).

 

PGT-A Procedure Steps

  1. Consultation – Review medical and fertility history, explain pgta test purpose.
  2. Embryo Culture – Embryos grown to the blastocyst stage under expert care.
  3. Blastocyst Biopsy – Laser-assisted cell extraction for genetic testing.
  4. Genetic Analysis – Cells undergo IVF genetic testing in the lab.
  5. Results Discussion – Interpretation of PGT-A report and continuation of IVF cycle.
  6. Embryo Transfer – Euploid embryos are transferred or cryopreserved.

Post-Procedure Care

  • Normal activity can be resumed immediately after biopsy.

  • Results are typically ready in a few days, followed by consultation with a fertility specialist.

  • Counseling is provided to explain embryo selection and next steps in IVF.

Risks and Considerations of PGT-A

Although pgta testing is safe and minimally invasive, patients should consider:

  • Mosaicism – Embryos may have both euploid and aneuploid cells, leading to potential false results.
  • Impact of embryo biopsy – Removal of 5–10 cells is generally safe but must be done by trained embryologists.
  • Accuracy limitations – No test guarantees 100%; PGT-A testing is part of a larger IVF genetic testing plan.
  • Genetic counseling – Recommended before and after pgta testing for correct interpretation and decision-making.

 

Success Rates of PGT-A

PGT-A testing can significantly enhance IVF success by transferring genetically normal embryos. At Kanaa Fertility Centre:

  • Higher implantation rates with euploid embryos identified via pgta test.

  • Lower miscarriage rates in patients with recurrent pregnancy loss or implantation failure.

  • Improved live birth rates compared to traditional IVF cycles without genetic analysis.

Our advanced pgta IVF lab and experienced embryologists ensure accurate genetic screening, improving success for couples planning a family.

Why Kanaa Fertility Centre for PGT-A?

  • Expert Embryologists – Specialists conducting pgta testing with precision.

  • State-of-the-Art Genetic Lab – Advanced facilities for safe IVF genetic testing.

  • Holistic Fertility Care – Counseling on preimplantation genetic testing, pgta test, and interpreting embryo genetic testing results.

  • Patient Support – Emotional and educational guidance throughout the PGT-A IVF process.

FAQs

Pre implantation genetic testing for aneuploidy refers to a process in which a few cells from the tropho ectoderm of the blastocyst are biopsied and sent for genetic analysis

Why is it done?
This will identify if the embryo is genetically normal (euploid) or genetically abnormal(aneuploid)

The embryo is formed by the process of IVF or ICSI as usual and allowed to grow till day 5.
Then a few cells (about 5-10) are removed by use of laser and sent for genetic analysis

It is the condition where more than one type of cells are present in the same embryo-that is both euploid and aneuploid cells hence there maybe the chance for false positive or false negative results depending on which cells were taken in the biopsy

It is advised for mainly older age couples, recurrent implantation failures, recurrent pregnancy loss. testing for specific gene disorders which run in the family-this is called as PGT-M.

Typically, results are available within a few days to a week after the embryo biopsy, depending on the lab and technology used.

Yes, when performed by skilled embryologists, the biopsy procedure is minimally invasive and safe, with negligible risk to the embryo’s development.

While PGT-A testing significantly improves chances by selecting euploid embryos, no test guarantees 100% success. IVF outcomes also depend on maternal health, uterine environment, and other factors.

PGT-A is incorporated during the embryo culture period (Day 5–6). While results may require embryo freezing for transfer in some cases, this does not significantly delay the overall treatment timeline.

PGT-A screens for chromosomal abnormalities (aneuploidy). For specific inherited single-gene disorders, PGT-M is used.

Yes, by identifying and selecting euploid embryos for transfer, PGT-A IVF reduces the likelihood of miscarriage related to chromosomal abnormalities.

The embryo biopsy is performed in the lab on the blastocyst; there is no pain for the patient. Standard IVF monitoring procedures may involve mild discomfort from blood draws or egg retrieval, but the PGT-A testing itself is not painful.

PGT-A is preimplantation, performed before embryo transfer, whereas prenatal genetic tests are performed on embryos or fetuses after implantation or during pregnancy.